{"entity_type":"fund","name":"Health Sciences Fund","identifiers":{"lei":"549300UTX0DZQILK4I63","cik":"1331971","fund_id":"S000034046","fundkey":"health-sciences-fund"},"dates":{"reporting_period_start":"2025-02-28","reporting_period_end":"2025-08-31","filing_date":"2025-04-28"},"summary":{"total_positions":201,"total_value_usd":102841057.92,"asset_categories":["STIV","DBT","EC","EP"],"by_asset_category":{"EC":{"positions":196,"total_value_usd":100543057},"STIV":{"positions":2,"total_value_usd":1323993.98},"EP":{"positions":1,"total_value_usd":504944.94},"DBT":{"positions":2,"total_value_usd":469062}}},"holdings":[{"issuer_name":"Eli Lilly and Company","title":"ELI LILLY and CO COMMON STOCK","isin":"US5324571083","value_usd":10580800.59,"pct_val":11.1936071467,"balance":11493,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Intuitive Surgical Inc.","title":"INTUITIVE SURGICAL INC COMMON STOCK USD.001","isin":"US46120E6023","value_usd":5897140.35,"pct_val":6.2386840963,"balance":10289,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"UnitedHealth Group Incorporated","title":"UNITEDHEALTH GROUP INC COMMON STOCK USD.01","isin":"US91324P1021","value_usd":5178013.92,"pct_val":5.4779081344,"balance":10902,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Thermo Fisher Scientific Inc.","title":"THERMO FISHER SCIENTIFIC INC COMMON STOCK USD1.0","isin":"US8835561023","value_usd":4450140.48,"pct_val":4.7078785634,"balance":8413,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Stryker Corporation","title":"STRYKER CORP COMMON STOCK USD.1","isin":"US8636671013","value_usd":4204836.72,"pct_val":4.4483675842,"balance":10888,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"argenx SE","title":"ARGENX SE ADR","isin":"US04016X1019","value_usd":3481285.91,"pct_val":3.6829109962,"balance":5573,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"NL","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Vertex Pharmaceuticals Incorporated","title":"VERTEX PHARMACEUTICALS INC COMMON STOCK USD.01","isin":"US92532F1003","value_usd":3000126.87,"pct_val":3.1738847441,"balance":6253,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Boston Scientific Corporation","title":"BOSTON SCIENTIFIC CORP COMMON STOCK USD.01","isin":"US1011371077","value_usd":2964865.14,"pct_val":3.1365807661,"balance":28566,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Danaher Corporation","title":"DANAHER CORP COMMON STOCK USD.01","isin":"US2358511028","value_usd":2710852.48,"pct_val":2.867856495,"balance":13048,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Alnylam Pharmaceuticals Inc.","title":"ALNYLAM PHARMACEUTICALS INC COMMON STOCK USD.01","isin":"US02043Q1076","value_usd":2302424.25,"pct_val":2.4357733917,"balance":9331,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"AstraZeneca PLC","title":"ASTRAZENECA PLC ADR","isin":"US0463531089","value_usd":2179758.42,"pct_val":2.3060031442,"balance":28602,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"GB","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Elevance Health Inc.","title":"ELEVANCE HEALTH INC COMMON STOCK USD.01","isin":"US0367521038","value_usd":1747462.64,"pct_val":1.8486701577,"balance":4403,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Regeneron Pharmaceuticals Inc.","title":"REGENERON PHARMACEUTICALS INC COMMON STOCK USD.001","isin":"US75886F1075","value_usd":1593127.2,"pct_val":1.6853960964,"balance":2280,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Insmed Incorporated","title":"INSMED INC COMMON STOCK USD.01","isin":"US4576693075","value_usd":1557605,"pct_val":1.6478165628,"balance":19100,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"BeiGene Ltd.","title":"BEIGENE LTD ADR USD.0001","isin":"US07725L1026","value_usd":1536485.4,"pct_val":1.6254737823,"balance":5653,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Novo Nordisk A/S","title":"NOVO NORDISK A/S ADR","isin":"US6701002056","value_usd":1533541.2,"pct_val":0.6752289067,"balance":14359,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"DK","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Merck and Co. Inc.","title":"MERCK and CO INC COMMON STOCK USD.5","isin":"US58933Y1055","value_usd":1507180.5,"pct_val":1.594471635,"balance":16338,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Amgen Inc.","title":"AMGEN INC COMMON STOCK USD.0001","isin":"US0311621009","value_usd":1415535.7,"pct_val":1.4975190576,"balance":4595,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"The Cigna Group","title":"CIGNA GROUP/THE COMMON STOCK USD.01","isin":"US1255231003","value_usd":1357704.6,"pct_val":1.4363385629,"balance":4396,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"State Street Bank and Trust Company","title":"SSC GOVERNMENT MM GVMXX 20301231 00001.0000000000","isin":null,"value_usd":1323893.98,"pct_val":0.5829197707,"balance":1323893.98,"units":"NS","currency":"USD","asset_cat":"STIV","issuer_cat":"RF","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Penumbra Inc.","title":"PENUMBRA INC COMMON STOCK USD.001","isin":"US70975L1070","value_usd":1309884.16,"pct_val":1.385748514,"balance":4589,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Blueprint Medicines Corporation","title":"BLUEPRINT MEDICINES CORP COMMON STOCK USD.001","isin":"US09627Y1091","value_usd":1149086.43,"pct_val":1.2156378873,"balance":11899,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Ascendis Pharma A/S","title":"ASCENDIS PHARMA A/S ADR DKK1.0","isin":"US04351P1012","value_usd":1012602.86,"pct_val":1.0712496199,"balance":6467,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"DK","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Summit Therapeutics Inc.","title":"SUMMIT THERAPEUTICS INC COMMON STOCK USD.01","isin":"US86627T1088","value_usd":964526.42,"pct_val":1.0203887443,"balance":46618,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Sanofi","title":"SANOFI SA ADR","isin":"US80105N1054","value_usd":960905.27,"pct_val":1.0165578688,"balance":17641,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"FR","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Hologic Inc.","title":"HOLOGIC INC COMMON STOCK USD.01","isin":"US4364401012","value_usd":903120,"pct_val":0.397650047,"balance":11360,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Becton Dickinson and Company","title":"BECTON DICKINSON and CO COMMON STOCK USD1.0","isin":"US0758871091","value_usd":877086.17,"pct_val":0.9278842312,"balance":3889,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Chugai Pharmaceutical Co. Ltd.","title":"CHUGAI PHARMACEUTICAL CO LTD COMMON STOCK","isin":"JP3519400000","value_usd":869012.88,"pct_val":0.9193433617,"balance":17300,"units":"NS","currency":null,"asset_cat":"EC","issuer_cat":"CORP","inv_country":"JP","fair_val_level":"2","payoff_profile":"Long"},{"issuer_name":"Verona Pharma PLC","title":"VERONA PHARMA PLC ADR","isin":"US9250501064","value_usd":779368.59,"pct_val":0.8245071575,"balance":11193,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"GB","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Humana Inc.","title":"HUMANA INC COMMON STOCK USD.1666666","isin":"US4448591028","value_usd":727020.14,"pct_val":0.320112048,"balance":2453,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"HCA Healthcare Inc.","title":"HCA HEALTHCARE INC COMMON STOCK USD.01","isin":"US40412C1018","value_usd":709697.1,"pct_val":0.7508005149,"balance":2317,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Sonova Holding AG","title":"SONOVA HOLDING AG COMMON STOCK CHF.05","isin":"CH0012549785","value_usd":708373.99,"pct_val":0.7494007745,"balance":2201,"units":"NS","currency":null,"asset_cat":"EC","issuer_cat":"CORP","inv_country":"CH","fair_val_level":"2","payoff_profile":"Long"},{"issuer_name":"Roche Holding AG","title":"ROCHE HOLDING AG COMMON STOCK","isin":"CH0012032048","value_usd":679048.23,"pct_val":0.7183765591,"balance":2039,"units":"NS","currency":null,"asset_cat":"EC","issuer_cat":"CORP","inv_country":"CH","fair_val_level":"2","payoff_profile":"Long"},{"issuer_name":"Gilead Sciences Inc.","title":"GILEAD SCIENCES INC COMMON STOCK USD.001","isin":"US3755581036","value_usd":649280.8,"pct_val":0.6868850936,"balance":5680,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Natera Inc.","title":"NATERA INC COMMON STOCK","isin":"US6323071042","value_usd":645854.09,"pct_val":0.6832599193,"balance":4151,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Scholar Rock Holding Corporation","title":"SCHOLAR ROCK HOLDING CORP COMMON STOCK USD.001","isin":"US80706P1030","value_usd":623837.4,"pct_val":0.6599680922,"balance":16070,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Molina Healthcare Inc.","title":"MOLINA HEALTHCARE INC COMMON STOCK USD.001","isin":"US60855R1005","value_usd":608864.64,"pct_val":0.6441281572,"balance":2022,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Tenet Healthcare Corporation","title":"TENET HEALTHCARE CORP COMMON STOCK USD.05","isin":"US88033G4073","value_usd":601682.27,"pct_val":0.636529807,"balance":4753,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Avidity Biosciences Inc.","title":"AVIDITY BIOSCIENCES INC COMMON STOCK","isin":"US05370A1088","value_usd":572968,"pct_val":0.6061524972,"balance":18700,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Neurocrine Biosciences Inc.","title":"NEUROCRINE BIOSCIENCES INC COMMON STOCK USD.001","isin":"US64125C1099","value_usd":557271.68,"pct_val":0.5895470959,"balance":4694,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Vaxcyte Inc.","title":"VAXCYTE INC COMMON STOCK USD.001","isin":"US92243G1085","value_usd":536112.84,"pct_val":0.5671628027,"balance":7342,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Revolution Medicines Inc.","title":"REVOLUTION MEDICINES INC COMMON STOCK","isin":"US76155X1000","value_usd":529782.96,"pct_val":0.560466316,"balance":13004,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Quest Diagnostics Incorporated","title":"QUEST DIAGNOSTICS INC COMMON STOCK USD.01","isin":"US74834L1008","value_usd":528555.3,"pct_val":0.5591675538,"balance":3057,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Zai Lab Limited","title":"ZAI LAB LTD ADR USD.00006","isin":"US98887Q1040","value_usd":523410.4,"pct_val":0.5537246775,"balance":15110,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"CN","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"IDEXX Laboratories Inc.","title":"IDEXX LABORATORIES INC COMMON STOCK USD.1","isin":"US45168D1046","value_usd":517101.13,"pct_val":0.5470499945,"balance":1183,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Sartorius Aktiengesellschaft","title":"SARTORIUS AG PREFERENCE","isin":"DE0007165631","value_usd":504944.94,"pct_val":0.5341897563,"balance":2015,"units":"NS","currency":null,"asset_cat":"EP","issuer_cat":"CORP","inv_country":"DE","fair_val_level":"2","payoff_profile":"Long"},{"issuer_name":"Biohaven Ltd.","title":"BIOHAVEN LTD COMMON STOCK","isin":"VGG1110E1079","value_usd":497951.74,"pct_val":0.5267915323,"balance":13393,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"United Therapeutics Corporation","title":"UNITED THERAPEUTICS CORP COMMON STOCK USD.01","isin":"US91307C1027","value_usd":496717.6,"pct_val":0.5254859148,"balance":1552,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Akero Therapeutics Inc.","title":"AKERO THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US00973Y1082","value_usd":468997.76,"pct_val":0.4961606292,"balance":9548,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"BioMarin Pharmaceutical Inc.","title":"BIOMARIN PHARMACEUTICAL INC COMMON STOCK USD.001","isin":"US09061G1013","value_usd":466237.83,"pct_val":0.2052877746,"balance":7061,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"MoonLake Immunotherapeutics","title":"MOONLAKE IMMUNOTHERAPEUTICS COMMON STOCK USD.0001","isin":"KY61559X1045","value_usd":463201.92,"pct_val":0.4900291124,"balance":11092,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"CH","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Tempus AI Inc.","title":"TEMPUS AI INC COMMON STOCK USD.0001","isin":"US88023B1035","value_usd":446955.19,"pct_val":0.1967974935,"balance":7141,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Exact Sciences Corporation","title":"EXACT SCIENCES CORP COMMON STOCK USD.01","isin":"US30063P1057","value_usd":427970.07,"pct_val":0.452756745,"balance":9027,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Arcellx Inc.","title":"ARCELLX INC COMMON STOCK USD.001","isin":"US03940C1009","value_usd":416144.4,"pct_val":0.4402461695,"balance":6420,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Centessa Pharmaceuticals plc","title":"CENTESSA PHARMACEUTICALS PLC ADR USD.0001","isin":"US1523091007","value_usd":412432.65,"pct_val":0.4363194467,"balance":26523,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Cardinal Health Inc.","title":"CARDINAL HEALTH INC COMMON STOCK","isin":"US14149Y1082","value_usd":405272.4,"pct_val":0.4287444976,"balance":3130,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Centene Corporation","title":"CENTENE CORP COMMON STOCK USD.001","isin":"US15135B1017","value_usd":385833.44,"pct_val":0.4081796944,"balance":6634,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Keros Therapeutics Inc.","title":"KEROS THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US4923271013","value_usd":372538.48,"pct_val":0.164031296,"balance":6452,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Revvity Inc.","title":"REVVITY INC COMMON STOCK USD1.0","isin":"US7140461093","value_usd":363029.55,"pct_val":0.3840550751,"balance":3237,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Krystal Biotech Inc.","title":"KRYSTAL BIOTECH INC COMMON STOCK USD.00001","isin":"US5011471027","value_usd":360292.5,"pct_val":0.3811595038,"balance":2010,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Agilent Technologies Inc.","title":"AGILENT TECHNOLOGIES INC COMMON STOCK USD.01","isin":"US00846U1016","value_usd":356896.8,"pct_val":0.3775671356,"balance":2790,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"CVS Health Corporation","title":"CVS HEALTH CORP COMMON STOCK USD.01","isin":"US1266501006","value_usd":353179.28,"pct_val":0.3736343086,"balance":5374,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Alkermes Public Limited Company","title":"ALKERMES PLC COMMON STOCK USD.01","isin":"IE00B56GVS15","value_usd":349822.7,"pct_val":0.3700833261,"balance":10190,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"IE","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Madrigal Pharmaceuticals Inc.","title":"MADRIGAL PHARMACEUTICALS INC COMMON STOCK USD.0001","isin":"US5588681057","value_usd":348095.4,"pct_val":0.3682559863,"balance":1020,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Bio-Techne Corporation","title":"BIO-TECHNE CORP COMMON STOCK USD.01","isin":"US09073M1045","value_usd":345367.75,"pct_val":0.3653703594,"balance":5593,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Ultragenyx Pharmaceutical Inc.","title":"ULTRAGENYX PHARMACEUTICAL INC COMMON STOCK USD.001","isin":"US90400D1081","value_usd":327393.76,"pct_val":0.3463553727,"balance":7628,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Masimo Corporation","title":"MASIMO CORP COMMON STOCK USD.001","isin":"US5747951003","value_usd":319398.84,"pct_val":0.3378974122,"balance":1692,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Veeva Systems Inc.","title":"VEEVA SYSTEMS INC COMMON STOCK USD.00001","isin":"US9224751084","value_usd":317830.52,"pct_val":0.33623826,"balance":1418,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"DexCom Inc.","title":"DEXCOM INC COMMON STOCK USD.001","isin":"US2521311074","value_usd":315480.9,"pct_val":0.3337525575,"balance":3570,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"SpringWorks Therapeutics Inc.","title":"SPRINGWORKS THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US85205L1070","value_usd":314792,"pct_val":0.3330237585,"balance":5450,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Cencora Inc.","title":"CENCORA INC COMMON STOCK USD.01","isin":"US03073E1055","value_usd":310840.04,"pct_val":0.3288429135,"balance":1226,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Agios Pharmaceuticals Inc.","title":"AGIOS PHARMACEUTICALS INC COMMON STOCK USD.001","isin":"US00847X1046","value_usd":307705.32,"pct_val":0.3255266404,"balance":8658,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Protagonist Therapeutics Inc.","title":"PROTAGONIST THERAPEUTICS INC COMMON STOCK USD.00001","isin":"US74366E1029","value_usd":300907.95,"pct_val":0.3183355882,"balance":8005,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Kymera Therapeutics Inc.","title":"KYMERA THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US5015751044","value_usd":295912.65,"pct_val":0.3130509762,"balance":9439,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Bruker Corporation","title":"BRUKER CORP COMMON STOCK USD.01","isin":"US1167941087","value_usd":295255.25,"pct_val":0.1300029498,"balance":5095,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Oscar Health Inc.","title":"OSCAR HEALTH INC COMMON STOCK USD.00001","isin":"US6877931096","value_usd":289935.45,"pct_val":0.3067275957,"balance":19845,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"McKesson Corporation","title":"MCKESSON CORP COMMON STOCK USD.01","isin":"US58155Q1031","value_usd":289397.52,"pct_val":0.3061585105,"balance":452,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"BrightSpring Health Services Inc.","title":"BRIGHTSPRING HEALTH SERVICES I COMMON STOCK USD100.0","isin":"US10950A1060","value_usd":288004.64,"pct_val":0.3046849592,"balance":14938,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Repligen Corporation","title":"REPLIGEN CORP COMMON STOCK USD.01","isin":"US7599161095","value_usd":285234.66,"pct_val":0.3017545508,"balance":1791,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Vera Therapeutics Inc.","title":"VERA THERAPEUTICS INC COMMON STOCK USD.001","isin":"US92337R1014","value_usd":281521.58,"pct_val":0.2978264209,"balance":9406,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Crinetics Pharmaceuticals Inc.","title":"CRINETICS PHARMACEUTICALS INC COMMON STOCK USD.001","isin":"US22663K1079","value_usd":274504.16,"pct_val":0.2904025741,"balance":7672,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Beam Therapeutics Inc.","title":"BEAM THERAPEUTICS INC COMMON STOCK USD.01","isin":"US07373V1052","value_usd":250967.52,"pct_val":0.2655027662,"balance":9528,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Incyte Corporation","title":"INCYTE CORP COMMON STOCK USD.001","isin":"US45337C1027","value_usd":240933,"pct_val":0.2548870785,"balance":3278,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Immunocore Holdings plc","title":"IMMUNOCORE HOLDINGS PLC SR UNSECURED 144A 02/30 2.5","isin":"US45258DAA37","value_usd":237553.2,"pct_val":0.104596334,"balance":276000,"units":"PA","currency":"USD","asset_cat":"DBT","issuer_cat":"CORP","inv_country":"GB","fair_val_level":"2","payoff_profile":"Long"},{"issuer_name":"Immunocore Holdings plc","title":"IMMUNOCORE HOLDINGS PLC ADR GBP.0001","isin":"US45258D1054","value_usd":237515.19,"pct_val":0.2512713197,"balance":8087,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"GB","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Procept Biorobotics Corporation","title":"PROCEPT BIOROBOTICS CORP COMMON STOCK USD.00001","isin":"US74276L1052","value_usd":235806.1,"pct_val":0.2494632447,"balance":3665,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Denali Therapeutics Inc.","title":"DENALI THERAPEUTICS INC COMMON STOCK USD.01","isin":"US24823R1059","value_usd":233032.32,"pct_val":0.2465288161,"balance":14072,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Immunocore Holdings plc","title":"IMMUNOCORE HOLDINGS PLC SR UNSECURED 02/30 2.5","isin":"US45258DAB10","value_usd":231508.8,"pct_val":0.2449170586,"balance":276000,"units":"PA","currency":"USD","asset_cat":"DBT","issuer_cat":"CORP","inv_country":"GB","fair_val_level":"2","payoff_profile":"Long"},{"issuer_name":"The Cooper Companies Inc.","title":"COOPER COS INC/THE COMMON STOCK USD.1","isin":"US2166485019","value_usd":227396.08,"pct_val":0.2405661429,"balance":2516,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Immatics N.V.","title":"IMMATICS NV COMMON STOCK","isin":"NL0015285941","value_usd":224298.88,"pct_val":0.0987603643,"balance":26959,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"DE","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"UCB SA","title":"UCB SA COMMON STOCK","isin":"BE0003739530","value_usd":203887.09,"pct_val":0.2156955864,"balance":1079,"units":"NS","currency":null,"asset_cat":"EC","issuer_cat":"CORP","inv_country":"BE","fair_val_level":"2","payoff_profile":"Long"},{"issuer_name":"Geron Corporation","title":"GERON CORP COMMON STOCK USD.001","isin":"US3741631036","value_usd":197817.68,"pct_val":0.0871005068,"balance":48014,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Pliant Therapeutics Inc.","title":"PLIANT THERAPEUTICS INC COMMON STOCK","isin":"US7291391057","value_usd":184878.6,"pct_val":0.0814033395,"balance":13397,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Edwards Lifesciences Corporation","title":"EDWARDS LIFESCIENCES CORP COMMON STOCK USD1.0","isin":"US28176E1082","value_usd":184135.02,"pct_val":0.1947995389,"balance":2571,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Immunome Inc.","title":"IMMUNOME INC COMMON STOCK USD.0001","isin":"US45257U1088","value_usd":179981.8,"pct_val":0.1904057775,"balance":19147,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Helix Acquisition Corp. II","title":"HELIX ACQUISITION CORP II COMMON STOCK USD.0001","isin":"KYG4444H1011","value_usd":179242.05,"pct_val":0.1896231835,"balance":16221,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"KY","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Biogen Inc.","title":"BIOGEN INC COMMON STOCK USD.0005","isin":"US09062X1037","value_usd":178716,"pct_val":0.1890666663,"balance":1272,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"IGM Biosciences Inc.","title":"IGM BIOSCIENCES INC COMMON STOCK USD.01","isin":"US4495851085","value_usd":178199.96,"pct_val":0.0784626876,"balance":17749,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Replimune Group Inc.","title":"REPLIMUNE GROUP INC COMMON STOCK USD.001","isin":"US76029N1063","value_usd":177126.92,"pct_val":0.1873855519,"balance":13969,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Legend Biotech Corporation","title":"LEGEND BIOTECH CORP ADR USD.0001","isin":"US52490G1022","value_usd":174244.77,"pct_val":0.1843364768,"balance":4977,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Lantheus Holdings Inc.","title":"LANTHEUS HOLDINGS INC COMMON STOCK USD.01","isin":"US5165441032","value_usd":168876,"pct_val":0.1786567646,"balance":1800,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Alignment Healthcare Inc.","title":"ALIGNMENT HEALTHCARE INC COMMON STOCK USD.001","isin":"US01625V1044","value_usd":164289.99,"pct_val":0.1738051474,"balance":10471,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Cytokinetics Incorporated","title":"CYTOKINETICS INC COMMON STOCK USD.001","isin":"US23282W6057","value_usd":162196,"pct_val":0.1715898801,"balance":3526,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Apogee Therapeutics Inc.","title":"APOGEE THERAPEUTICS INC COMMON STOCK USD.00001","isin":"US03770N1019","value_usd":157797.36,"pct_val":0.1669364848,"balance":5019,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Nuvalent Inc.","title":"NUVALENT INC COMMON STOCK USD.0001","isin":"US6707031075","value_usd":156483.26,"pct_val":0.1655462763,"balance":2087,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Ionis Pharmaceuticals Inc.","title":"IONIS PHARMACEUTICALS INC COMMON STOCK USD.001","isin":"US4622221004","value_usd":152541.24,"pct_val":0.1613759469,"balance":4596,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Disc Medicine Inc.","title":"DISC MEDICINE INC COMMON STOCK USD.0001","isin":"US2546041011","value_usd":146966.88,"pct_val":0.1554787376,"balance":2616,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Moderna Inc.","title":"MODERNA INC COMMON STOCK USD.0001","isin":"US60770K1079","value_usd":137792,"pct_val":0.0606707805,"balance":3200,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Janux Therapeutics Inc.","title":"JANUX THERAPEUTICS INC COMMON STOCK USD.001","isin":"US47103J1051","value_usd":127317.19,"pct_val":0.1346909996,"balance":3871,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Neumora Therapeutics Inc.","title":"NEUMORA THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US6409791000","value_usd":119240.24,"pct_val":0.0525023109,"balance":11996,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Metsera Inc.","title":"METSERA INC COMMON STOCK USD.00001","isin":"US59267L1070","value_usd":116961.6,"pct_val":0.1237356465,"balance":4720,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Merus N.V.","title":"MERUS NV COMMON STOCK EUR.05","isin":"NL0011606264","value_usd":116171.03,"pct_val":0.1228992892,"balance":2467,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"NL","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Icon Public Limited Company","title":"ICON PLC COMMON STOCK EUR.06","isin":"IE0005711209","value_usd":115912.2,"pct_val":0.1226254686,"balance":610,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"IE","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Bicycle Therapeutics plc","title":"BICYCLE THERAPEUTICS PLC ADR USD.01","isin":"US0887861088","value_usd":115755.44,"pct_val":0.1224596295,"balance":10552,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"GB","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Wave Life Sciences Ltd.","title":"WAVE LIFE SCIENCES LTD COMMON STOCK","isin":"SG9999014716","value_usd":114134.86,"pct_val":0.1207451907,"balance":10798,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Rhythm Pharmaceuticals Inc.","title":"RHYTHM PHARMACEUTICALS INC COMMON STOCK","isin":"US76243J1051","value_usd":113883.34,"pct_val":0.1204791034,"balance":2074,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Tarsus Pharmaceuticals Inc.","title":"TARSUS PHARMACEUTICALS INC COMMON STOCK USD.0001","isin":"US87650L1035","value_usd":111644.8,"pct_val":0.1181109142,"balance":2510,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Celldex Therapeutics Inc.","title":"CELLDEX THERAPEUTICS INC COMMON STOCK USD.001","isin":"US15117B2025","value_usd":107478.25,"pct_val":0.1137030508,"balance":5225,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"ARS Pharmaceuticals Inc.","title":"ARS PHARMACEUTICALS INC COMMON STOCK USD.0001","isin":"US82835W1080","value_usd":105923,"pct_val":0.0466386371,"balance":7300,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"CG Oncology Inc.","title":"CG ONCOLOGY INC COMMON STOCK","isin":"US1569441009","value_usd":99690.3,"pct_val":0.1054640474,"balance":3855,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"BioAge Labs Inc.","title":"BIOAGE LABS INC COMMON STOCK USD.00001","isin":"US09077V1008","value_usd":98192.4,"pct_val":0.0432347999,"balance":5223,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Sensorion","title":"SENSORION SA COMMON STOCK EUR.1","isin":"FR0012596468","value_usd":97321.18,"pct_val":0.1029577154,"balance":155874,"units":"NS","currency":null,"asset_cat":"EC","issuer_cat":"CORP","inv_country":"FR","fair_val_level":"2","payoff_profile":"Long"},{"issuer_name":"Zentalis Pharmaceuticals Inc.","title":"ZENTALIS PHARMACEUTICALS INC COMMON STOCK USD.001","isin":"US98943L1070","value_usd":97307.55,"pct_val":0.0428451942,"balance":26955,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"GeneDx Holdings Corp.","title":"GENEDX HOLDINGS CORP COMMON STOCK USD.0001","isin":"US81663L2007","value_usd":91947.9,"pct_val":0.097273232,"balance":894,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Praxis Precision Medicines Inc.","title":"PRAXIS PRECISION MEDICINES INC COMMON STOCK USD.0001","isin":"US74006W2070","value_usd":91404.8,"pct_val":0.0966986774,"balance":2368,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"MacroGenics Inc.","title":"MACROGENICS INC COMMON STOCK USD.01","isin":"US5560991094","value_usd":90697.76,"pct_val":0.0399348575,"balance":25264,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Xencor Inc.","title":"XENCOR INC COMMON STOCK USD.01","isin":"US98401F1057","value_usd":89932.8,"pct_val":0.0951414238,"balance":5855,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Bicara Therapeutics Inc.","title":"BICARA THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US0554771032","value_usd":86928.8,"pct_val":0.0919634416,"balance":6536,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"MBX Biosciences Inc.","title":"MBX BIOSCIENCES INC COMMON STOCK USD.0001","isin":"US55287L1017","value_usd":86774.4,"pct_val":0.0918000992,"balance":9039,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Rocket Pharmaceuticals Inc.","title":"ROCKET PHARMACEUTICALS INC COMMON STOCK USD.01","isin":"US77313F1066","value_usd":85966.65,"pct_val":0.0909455669,"balance":9097,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Soleno Therapeutics Inc.","title":"SOLENO THERAPEUTICS INC COMMON STOCK USD.001","isin":"US8342033094","value_usd":85581.46,"pct_val":0.0905380679,"balance":1753,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Sionna Therapeutics Inc.","title":"SIONNA THERAPEUTICS INC COMMON STOCK USD.001","isin":"US8294011080","value_usd":81311.85,"pct_val":0.0860211756,"balance":5905,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"ORIC Pharmaceuticals Inc.","title":"ORIC PHARMACEUTICALS INC COMMON STOCK USD.0001","isin":"US68622P1093","value_usd":78999.14,"pct_val":0.0835745207,"balance":9838,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Corbus Pharmaceuticals Holdings Inc.","title":"CORBUS PHARMACEUTICALS HOLDING COMMON STOCK USD.0001","isin":"US21833P3010","value_usd":78408,"pct_val":0.0345235903,"balance":4400,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Autolus Therapeutics plc","title":"AUTOLUS THERAPEUTICS PLC ADR GBP.0000001","isin":"US05280R1005","value_usd":77933.68,"pct_val":0.0343147439,"balance":23474,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"GB","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Arvinas Inc.","title":"ARVINAS INC COMMON STOCK USD.001","isin":"US04335A1051","value_usd":77490.6,"pct_val":0.0819786108,"balance":4378,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Prothena Corporation Public Limited Company","title":"PROTHENA CORP PLC COMMON STOCK USD.01","isin":"IE00B91XRN20","value_usd":77279.28,"pct_val":0.0817550519,"balance":4888,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"IE","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"NovoCure Limited","title":"NOVOCURE LTD COMMON STOCK","isin":"JE00BYSS4X48","value_usd":77138.15,"pct_val":0.0816057481,"balance":4045,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"JE","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"BioNTech SE","title":"BIONTECH SE ADR","isin":"US09075V1026","value_usd":76221,"pct_val":0.0806354796,"balance":675,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"DE","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Pharvaris N.V.","title":"PHARVARIS NV COMMON STOCK EUR.12","isin":"NL00150005Y4","value_usd":75604.5,"pct_val":0.0799832739,"balance":4755,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"NL","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Structure Therapeutics Inc.","title":"STRUCTURE THERAPEUTICS INC ADR USD.0001","isin":"US86366E1064","value_usd":73363.75,"pct_val":0.0776127467,"balance":3089,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Edgewise Therapeutics Inc.","title":"EDGEWISE THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US28036F1057","value_usd":73276,"pct_val":0.0775199145,"balance":2800,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Beta Bionics Inc.","title":"BETA BIONICS INC COMMON STOCK USD.0001","isin":"US08659B1026","value_usd":70312.41,"pct_val":0.0743846827,"balance":3353,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Encompass Health Corporation","title":"ENCOMPASS HEALTH CORP COMMON STOCK USD.01","isin":"US29261A1007","value_usd":69697.44,"pct_val":0.0737340956,"balance":696,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Sagimet Biosciences Inc.","title":"SAGIMET BIOSCIENCES INC COMMON STOCK USD.0001","isin":"US7867001049","value_usd":69418,"pct_val":0.0305652305,"balance":12200,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Gossamer Bio Inc.","title":"GOSSAMER BIO INC COMMON STOCK USD.0001","isin":"US38341P1021","value_usd":69086.07,"pct_val":0.0304190794,"balance":98963,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Rapport Therapeutics Inc.","title":"RAPPORT THERAPEUTICS INC COMMON STOCK USD.001","isin":"US75383L1026","value_usd":64262.21,"pct_val":0.0679840743,"balance":6407,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Allogene Therapeutics Inc.","title":"ALLOGENE THERAPEUTICS INC COMMON STOCK USD.001","isin":"US0197701065","value_usd":64055.55,"pct_val":0.0677654452,"balance":32849,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Monte Rosa Therapeutics Inc.","title":"MONTE ROSA THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US61225M1027","value_usd":63052,"pct_val":0.0667037727,"balance":11464,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Spyre Therapeutics Inc.","title":"SPYRE THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US00773J2024","value_usd":61089.7,"pct_val":0.0646278225,"balance":3101,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Sana Biotechnology Inc.","title":"SANA BIOTECHNOLOGY INC COMMON STOCK USD.0001","isin":"US7995661045","value_usd":57874.14,"pct_val":0.0612260274,"balance":22174,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Iovance Biotherapeutics Inc.","title":"IOVANCE BIOTHERAPEUTICS INC COMMON STOCK USD.000041666","isin":"US4622601007","value_usd":56431.38,"pct_val":0.0596997073,"balance":13325,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"LENZ Therapeutics Inc.","title":"LENZ THERAPEUTICS INC COMMON STOCK USD.00001","isin":"US52635N1037","value_usd":55426.37,"pct_val":0.0586364903,"balance":2539,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Aura Biosciences Inc.","title":"AURA BIOSCIENCES INC COMMON STOCK USD.00001","isin":"US05153U1079","value_usd":55231.26,"pct_val":0.0584300802,"balance":7374,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"10x Genomics Inc.","title":"10X GENOMICS INC COMMON STOCK USD.00001","isin":"US88025U1097","value_usd":54444.17,"pct_val":0.0575974044,"balance":5093,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Terns Pharmaceuticals Inc.","title":"TERNS PHARMACEUTICALS INC COMMON STOCK USD.0001","isin":"US8808811074","value_usd":54094.56,"pct_val":0.0238182128,"balance":8669,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Viridian Therapeutics Inc","title":"VIRIDIAN THERAPEUTICS INC COMMON STOCK USD.01","isin":"US92790C1045","value_usd":53904.63,"pct_val":0.0570266159,"balance":3471,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Relay Therapeutics Inc.","title":"RELAY THERAPEUTICS INC COMMON STOCK USD.001","isin":"US75943R1023","value_usd":51603.53,"pct_val":0.0545922435,"balance":15133,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Hims and Hers Health Inc.","title":"HIMS and HERS HEALTH INC COMMON STOCK USD.0001","isin":"US4330001060","value_usd":50185.17,"pct_val":0.0530917366,"balance":1113,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"IDEAYA Biosciences Inc.","title":"IDEAYA BIOSCIENCES INC COMMON STOCK","isin":"US45166A1025","value_usd":50149.66,"pct_val":0.0530541699,"balance":2438,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Sage Therapeutics Inc.","title":"SAGE THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US78667J1088","value_usd":49848.11,"pct_val":0.0219484712,"balance":9113,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"EyePoint Pharmaceuticals Inc.","title":"EYEPOINT PHARMACEUTICALS INC COMMON STOCK USD.01","isin":"US30233G2093","value_usd":49746.18,"pct_val":0.0526273217,"balance":7934,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Oruka Therapeutics Inc.","title":"ORUKA THERAPEUTICS INC COMMON STOCK USD.001","isin":"US6876041087","value_usd":47471.55,"pct_val":0.0502209523,"balance":4677,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Korro Bio Inc.","title":"KORRO BIO INC COMMON STOCK USD.001","isin":"US5009461089","value_usd":46854,"pct_val":0.0206301436,"balance":900,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Lyell Immunopharma Inc.","title":"LYELL IMMUNOPHARMA INC COMMON STOCK USD.0001","isin":"US55083R1041","value_usd":46308.62,"pct_val":0.048990669,"balance":65150,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Heron Therapeutics Inc.","title":"HERON THERAPEUTICS INC COMMON STOCK USD.01","isin":"US4277461020","value_usd":45695,"pct_val":0.0483415101,"balance":18500,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"UroGen Pharma Ltd.","title":"UROGEN PHARMA LTD COMMON STOCK USD.01","isin":"IL0011407140","value_usd":44462,"pct_val":0.0470370986,"balance":4700,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Alto Neuroscience Inc.","title":"ALTO NEUROSCIENCE INC COMMON STOCK USD.0001","isin":"US02157Q1094","value_usd":43059.24,"pct_val":0.0189592843,"balance":9764,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Voyager Therapeutics Inc.","title":"VOYAGER THERAPEUTICS INC COMMON STOCK USD.001","isin":"US92915B1061","value_usd":42746.16,"pct_val":0.0452218826,"balance":10477,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Entrada Therapeutics Inc","title":"ENTRADA THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US29384C1080","value_usd":42589.98,"pct_val":0.0450566571,"balance":3567,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Ocular Therapeutix Inc.","title":"OCULAR THERAPEUTIX INC COMMON STOCK USD.0001","isin":"US67576A1007","value_usd":41461.98,"pct_val":0.0438633269,"balance":5807,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Septerna Inc.","title":"SEPTERNA INC COMMON STOCK USD.001","isin":"US81734D1046","value_usd":40004.01,"pct_val":0.0423209159,"balance":6183,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Kodiak Sciences Inc.","title":"KODIAK SCIENCES INC COMMON STOCK USD.0001","isin":"US50015M1099","value_usd":39299.82,"pct_val":0.0415759415,"balance":9562,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Orchestra Biomed Holdings Inc.","title":"ORCHESTRA BIOMED HOLDINGS INC COMMON STOCK USD.0001","isin":"US68572M1062","value_usd":37993.69,"pct_val":0.0401941645,"balance":8101,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Apellis Pharmaceuticals Inc.","title":"APELLIS PHARMACEUTICALS INC COMMON STOCK USD.0001","isin":"US03753U1060","value_usd":37096.25,"pct_val":0.0392447477,"balance":1475,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Pacific Biosciences of California Inc.","title":"PACIFIC BIOSCI OF CALIFORNIA COMMON STOCK USD.0001","isin":"US69404D1081","value_usd":36743,"pct_val":0.0388710385,"balance":25340,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Cullinan Therapeutics Inc.","title":"CULLINAN THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US2300311063","value_usd":36099.48,"pct_val":0.0381902479,"balance":4252,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Neurogene Inc.","title":"NEUROGENE INC COMMON STOCK USD.000001","isin":"US64135M1053","value_usd":35380,"pct_val":0.0374290979,"balance":2000,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Day One Biopharmaceuticals Inc.","title":"DAY ONE BIOPHARMACEUTICALS INC COMMON STOCK USD.0001","isin":"US23954D1090","value_usd":34379.24,"pct_val":0.0151374196,"balance":2468,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Annexon Inc.","title":"ANNEXON INC COMMON STOCK","isin":"US03589W1027","value_usd":33630.96,"pct_val":0.035578759,"balance":12739,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Immuneering Corporation","title":"IMMUNEERING CORP COMMON STOCK USD.001","isin":"US45254E1073","value_usd":33617.1,"pct_val":0.0355640963,"balance":20374,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Third Harmonic Bio Inc.","title":"THIRD HARMONIC BIO INC COMMON STOCK USD.0001","isin":"US88427A1079","value_usd":33137.72,"pct_val":0.0145907697,"balance":2597,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"AnaptysBio Inc.","title":"ANAPTYSBIO INC COMMON STOCK USD.001","isin":"US0327241065","value_usd":32950.38,"pct_val":0.034858762,"balance":1959,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Dyne Therapeutics Inc.","title":"DYNE THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US26818M1080","value_usd":32269.31,"pct_val":0.0341382465,"balance":2371,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"MediWound Ltd","title":"MEDIWOUND LTD COMMON STOCK ILS.01","isin":"IL0011316309","value_usd":31108.4,"pct_val":0.0329101003,"balance":1874,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"IL","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Generation Bio Co.","title":"GENERATION BIO CO COMMON STOCK USD.0001","isin":"US37148K1007","value_usd":26443.94,"pct_val":0.0279754895,"balance":45593,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"C4 Therapeutics Inc.","title":"C4 THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US12529R1077","value_usd":25935,"pct_val":0.0114193617,"balance":5700,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Kyverna Therapeutics Inc.","title":"KYVERNA THERAPEUTICS INC COMMON STOCK USD.00001","isin":"US5019761049","value_usd":25525.92,"pct_val":0.0270043007,"balance":8988,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Alector Inc.","title":"ALECTOR INC COMMON STOCK USD.0001","isin":"US0144421072","value_usd":24891.92,"pct_val":0.0263335814,"balance":15178,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Applied Therapeutics Inc.","title":"APPLIED THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US03828A1016","value_usd":22939,"pct_val":0.010100202,"balance":11300,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Cabaletta Bio Inc.","title":"CABALETTA BIO INC COMMON STOCK USD.00001","isin":"US12674W1099","value_usd":18766.59,"pct_val":0.0198534916,"balance":10397,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Ginkgo Bioworks Holdings Inc.","title":"GINKGO BIOWORKS HOLDINGS INC COMMON STOCK USD.0001","isin":"US37611X2099","value_usd":18762.48,"pct_val":0.0198491436,"balance":2277,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Enanta Pharmaceuticals Inc.","title":"ENANTA PHARMACEUTICALS INC COMMON STOCK USD.01","isin":"US29251M1062","value_usd":18672,"pct_val":0.0197534233,"balance":2400,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"CARGO Therapeutics Inc.","title":"CARGO THERAPEUTICS INC COMMON STOCK USD.001","isin":"US14179K1016","value_usd":17104.24,"pct_val":0.0180948636,"balance":4549,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Prelude Therapeutics Incorporated","title":"PRELUDE THERAPEUTICS INC COMMON STOCK USD.0001","isin":"US74065P1012","value_usd":13049.49,"pct_val":0.0138052753,"balance":17193,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Climb Bio Inc.","title":"CLIMB BIO INC COMMON STOCK USD.0001","isin":"US28658R1068","value_usd":11455,"pct_val":0.0121184374,"balance":7900,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Benitec Biopharma Inc.","title":"BENITEC BIOPHARMA INC COMMON STOCK","isin":"US08205P2092","value_usd":9676.31,"pct_val":0.0042605469,"balance":959,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"GeneDx Holdings Corp.","title":"GENEDX HOLDINGS CORP GENEDX HOLDINGS CORP","isin":"US81663L1199","value_usd":2001.29,"pct_val":0.0021171984,"balance":7150,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"Revolution Medicines Inc.","title":"REVOLUTION MEDICINES INC WARRANTS CALL EXP 17DEC26","isin":"US76155X1182","value_usd":561.06,"pct_val":0.0005935548,"balance":6524,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"},{"issuer_name":"SomaLogic Inc.","title":"SOMALOGIC INC WARRANTS CALL EXP 31AUG26","isin":"US83444K1135","value_usd":292.9,"pct_val":0.0003098638,"balance":2900,"units":"NS","currency":"USD","asset_cat":"EC","issuer_cat":"CORP","inv_country":"US","fair_val_level":"3","payoff_profile":"Long"},{"issuer_name":"ROWE T PRICE GOV RES FD 20340919 00000.0000000000","title":"ROWE T PRICE GOV RES FD 20340919 00000.0000000000","isin":"US76105Y1091","value_usd":100,"pct_val":0.0001057917,"balance":100,"units":"NS","currency":"USD","asset_cat":"STIV","issuer_cat":"RF","inv_country":"US","fair_val_level":"1","payoff_profile":"Long"}],"source_documents":[{"label":"SEC NPORT-P Filings","url":"https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=1331971&type=NPORT&dateb=&owner=exclude&count=40"}],"dataset":{"json":"https://dealcharts.org/llm/facts/fund/health-sciences-fund.json","page":"https://dealcharts.org/capitalmarkets/funds/health-sciences-fund/"},"provenance":{"curator":"CMD+RVL","curator_url":"https://cmdrvl.com","platform":"Dealcharts","platform_url":"https://dealcharts.org/","source":"SEC NPORT-P Public Filings","license":"CC-BY 4.0","license_url":"https://creativecommons.org/licenses/by/4.0/","attribution":"Data curated by CMD+RVL from SEC NPORT-P public filings"},"citation":"Fund: Health Sciences Fund | LEI: 549300UTX0DZQILK4I63 | 201 positions totaling $102,841,058 across STIV, DBT, EC, EP | Filing: Sun Apr 27 2025 20:00:00 GMT-0400 (Eastern Daylight Time) | Source: SEC NPORT-P via Dealcharts.org","updated_at":"2025-04-28"}